Quiet sleep is for repair, active sleep is for learning

睡眠被认为可以实现许多不同的功能，从清除大脑废物到调节情绪和知觉。在动物模型中了解睡眠功能一直很困难，因为睡眠通常被减少到一种单一的状态。我们在果蝇中发现了不同的睡眠阶段，这为研究不同保守的睡眠功能是如何调节的提供了强有力的方法。这个项目将使用新的策略来操纵果蝇的睡眠阶段，以了解它们各自的生理和功能。我们将检验我们的假设，即不同类别的睡眠功能已被进化划分为不同的阶段：主要与大脑修复有关的安静阶段和对学习至关重要的活跃阶段。

Sleep is thought to achieve many different functions, from brain waste clearance to regulating emotions and perception. Understanding sleep functions in animal models has been difficult because sleep has been typically reduced to a single state. Our discovery of distinct sleep stages in the fruit fly provides a powerful way to study how different conserved sleep functions are regulated. This project will use new strategies for manipulating sleep stages in flies to understand their respective physiology and functions. We will test our hypothesis that different categories of sleep functions have been segregated by evolution into different stages: a quiet stage concerned primarily with brain repair and an active stage important for learning.