The Study of Total Body Potassium in Hypertensive patients

本文通过测定高血压病患者的全血钾和血清钾，探讨高血压病患者钾平衡的异常。高血压病患者噻嗪类药物治疗期间室性早搏发生率高，全身钾水平低，长期治疗60个月，血清钾水平无明显下降。虽然全身钾水平在24个月的长期治疗期间没有显著变化，但与对照组相比，噻嗪治疗超过24个月后观察到TBK显著降低。本文研究了氯化钾、葡萄糖酸钾和螺内酯对噻嗪类药物治疗中TBK和血清K的影响。只有螺内酯（75毫克/天）增加总身体钾和血清钾噻嗪治疗期间。

The abnormality of potussium balance in essential hypertensive patients was studied by the measurement of total body potassium and serum potassium.The value of total body potassium in essential hypertension was lower than normal patients. The frequency of ventricular premature beats in hypertensive patients during thiazide treatment was high in low value of total body potassium.No significant decrease of serum potassium level was abserned during 60 months long term theropy. Although the levels of total body potassium did not change significantly during 24 months long term therapy, significant decrease of TBK was observed with thiazide therapy for more than 24 months as compared to that in the control group. The effect of potassium chloride potassium gluconate and spironolactone on the TBK and serum K during thiazide treatment was studied. Only spironolactone (75 mg/day) increased total body potassium and serium potassium during thiazide treatment.