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日本人の寿命、疾病発症と遺伝環境の因子効果に関する比較衛生学的研究

日本人の寿命、疾病発症と遺伝環境の因子効果に関する比較衛生学的研究
日本人寿命、疾病发生以及遗传和环境因素影响的比较卫生学研究
批准号:
62440035
负责人:
KONDO Haruo
金额:
$9.47万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for General Scientific Research (A)
财政年份:
1987
资助国家:
日本
项目状态:
已结题
起止时间:
1987 至 1989

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中文摘要
翻译
我们根据我们原有的健康风险评估程序对各种体检结果进行了分析。该节目是根据日本人的流行病学数据制作的。总体而言,成人患病的风险与饮酒、吸烟等基本生活习惯有关,再次确认了其对健康的不良影响的重要性。证明了健康风险评估体系与个体系统相结合在延年益寿、预防疾病方面是有效的,每个风险项目都需要建立适当的观察期才能取得良好的实际效果。对身高的腹围进行回归分析,回归贡献系数约为0.55。因此,即使对于正常体型的人,也建议额外测量他们的腹围对于早期发现健康障碍很重要。日本吸烟者的相对百分比低于韩国。相反,在日本,每天吸烟超过21支的人的比例更高。对日本人淋巴细胞免疫遗传特性的实验显示,年龄对T细胞亚群的分布有影响。日本人的人类白细胞抗原(人类白细胞抗原)的组成呈现出很有特色的模式。例如,在I类抗原之一的人类白细胞抗原-A中,A2和A24的出现比例远远高于其他抗原。这一事实在器官种植中非常重要,因为A2抗原的匹配在捐赠者和接受者之间很重要。结果表明,日本人存在包括连锁不平衡在内的一些特有的人类白细胞抗原模式。
英文摘要
We analyzed results of various medical examinations by our original health risk appraisal program. The program was made on epidemiological data of Japanese people. On the whole, the risk of having adult diseases was related to fundamental life practice such as drinking or smoking, and we reconfirm the importance of their bad influence on our health.It was proved that the combination of the health risk appraisal system and individual systems are effective in prolonging life and preventing diseases, and that establishment of proper observation period is necessary for every risk item to get good practical results.The regression analysis of vental girth by height proved that the contribution coefficient of regression is about 0.55. It is therefore suggested even to people of normal build that additional measurement of their vental girth is important for early detection of health disorder.The relative percentage of smokers were lower in Japan than in Korea. Instead the percentage of smokers who take more than 21 cigarettes a day were higher in Japan.Experiments on immuno-hereditary characteristics of Japanese people with human lymphocyte revealed effects of aging on the distribution of T-cell subsets. And the composition of HLA(Human Leucocyte Antigen) in the Japanese showed very characteristic pattern. For instance, in HLA-A antigen, one of class I antigens, the appearance ratio of A2 and A24 were much higher than that of other antigens. The fact is very important on organ plantations, because the matching of A2 antigen is important between a donor and a recipient. Japanese people proved to have some characteristic pattern of HLA including linkage disequilibrium.
期刊论文(14)
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会议论文
近藤東郎: 病態生理. 6. 472-474 (1987)
近藤托罗:病理生理学。6. 472-474 (1987)
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通讯作者:
近藤東郎: "集団と個人のライフスタイルと心身健康" 健康管理. 401. 4-8 (1987)
Toro Kondo:“群体和个人生活方式与身心健康”健康管理。401. 4-8 (1987)。
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通讯作者:
近藤東郎: "成人病の発見から管理ー健康診断の効用と限界ー" 臨床成人病. 19. 27-31 (1989)
Toro Kondo:“成人疾病的检测和管理 - 健康检查的实用性和局限性”临床成人疾病 19. 27-31 (1989)。
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近藤東郎: "健康危険度予測の健康教育への導入" MOdern Physician. 8. 1397-1400 (1988)
Toro Kondo:“将健康风险预测引入健康教育”现代医师 8. 1397-1400 (1988)。
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共 14 条
    Development of arteriosclerosis marker for health promotion and detection
    • 批准号:
      60480194
    • 项目类别:
      Grant-in-Aid for General Scientific Research (B)
    • 资助金额:
      $4.03万
    • 财政年份:
      1985
    • 负责人:
      KONDO Haruo
    • 依托单位:
    海外基金