Synsthesis of tetra thionate salts and its redox reaction

1. 发现四硫酸盐离子在中性和酸性溶液中都是稳定的，可以作为滴定剂。用碘酸钾在盐酸中安培滴定法测定四硫酸盐离子。采用离子色谱法和安培滴定法研究了巯基化合物与四硫酸盐离子的氧化还原反应过程。半胱氨酸和青霉胺的测定采用四硫酸钾在+0.75 V vs. SCE.5下旋转玻碳电极进行安培滴定。建立了紫外检测器非抑制离子色谱法测定半胱氨酸、青霉胺、半胱氨酸、谷氨酸等硫醇类化合物的灵敏方法。巯基化合物与四硫酸盐离子反应生成硫代硫酸盐离子，用葡萄糖酸盐洗脱液或磷酸盐洗脱液用IC法定量测定生成的硫代硫酸盐离子。

1. It is found that tetrathionate ion was stable in neutral and acidic solutions, and it can be used as a titrant.2. Tetrathionate ion was determined with potassium iodate by amperometric titration in hydrochloric acid.3. Redox reaction process of thiol compounds with tetrathionate ion was investigated by ion chromatography and amperometric titration.4. Determination of cysteine and penicillamine was achieved by amperometric titration with potassium tetrathionate using a rotating glassy carbon electrode at +0.75 V vs. SCE.5. A sensitive method for determination of thiol compounds(cysteine,penicillamine, cysteamine, glutatione etc.) was developed by nonsuppressed ion chromatography with UV detector. Thiol compound is converted to thiosulfate ion by reaction with tetrathionate ion and the thiosulfate ion evolved is quantitatively determined by IC using gluconate eluent or phosphate eluent.