Developing innovative contact lens designs and materials for effective and safe corneal refractive reshaping

尽管屈光不正越来越普遍，但屈光不正矫正的选择有限。角膜塑形术是一种暂时减少屈光不正的角膜重塑技术，目前用于角膜塑形术的隐形眼镜设计仅对低至中度近视（近视）有效。在这个项目中，我们将采用创新的镜片设计方法，利用晶状体后泪膜产生的流体力，调节角膜组织对这些压力的反应，开发新型隐形眼镜设计，采用适当的镜片材料，有效和安全地进行角膜重塑，以纠正各种屈光不正。

Despite the increasing prevalence of refractive errors, there are limited options available for refractive error correction. Current contact lens designs for orthokeratology, a corneal reshaping technique which temporarily reduces refractive error, are effective for correcting only low to moderate myopia (short-sightedness). In this project, we will use innovative lens design approaches that harness the fluid forces generated in the post-lens tear film, and modulation of the corneal tissue response to these pressures, to develop novel contact lens designs in appropriate lens materials for effective and safe corneal reshaping to correct a wide range of refractive errors.