DEVELOPMENT OF A MONITORING SYSTEM OF CLINICAL INFORMATION,INTEGRATED WITH HOSPITAL INFORMATION SYSTEM

(1)内科症候知识库的精化和医学术语匹配算法的开发我们开发了一个专门用于内科知识库精化的知识库编辑器，即前一年开发的知识库。使用该知识库编辑器，分析症状特征的表示，并将知识库中使用的症状的表示归类为相似的组。提出了一种医学术语的语义匹配算法，对医学术语进行分组。该算法基于一种将一个复杂的术语分解成几个语义原始术语的技术。为了应用这个算法，我们还利用我们医院信息系统的主数据库和医学电子词典开发了一个基本的医学术语集。(2)根据症状生成疾病假说系统的实验开发在上述知识库中，我们开发了一个根据症状生成疾病假说的原型系统。通过…利用医院信息系统原型系统中存储的临床数据，对医院信息系统中存储的临床事件进行监测，并对医院信息系统中存储的临床检查结果进行报警报告。该系统由三个子系统组成：第一个是规则库系统，用于在某个时间满足一定的临床结果时激活预先定义的操作；第二个是监视规则库的系统；第三个是从医院信息系统中提取必要的数据目录的子系统。(4)基于HL7的监护系统与医院信息系统之间的消息通信系统我们尝试实现了美国使用的HL7消息通信协议的日文版，这是日本的第一次实际试验。上述推理机工作在Unix工作站上，医院信息系统使用修改后的HL7消息通信协议传输进行推理所需的信息。较少

(1) Refinement of symptom-disease knowledge-base in internal medicine domain, and a development of algorithm for matching medical termsWe developed a specific knowledge-base (KB) editor for the refinement of the KB in internal medicine, the KB which was developed in the previous year. Using this KB editor, representation of symptom characteristics are analyzed, and that of symptoms used in the KB are categorized into similar groups. Algorithm for matching semantics of medical terms was developed to make groups of the terms. This algorithm is based a technique of breaking a complicated term into several semantically primitive terms. To apply this algorithm, a basic set of medical terms is also developed using a master database of our hospital information system and Medical Electronic Dictionary.(2) A experimental development of a system which generates disease hypotheses from symptomsUsin the above KB,we developed a prototype system which generates disease hypotheses from symptoms. Thro … More ugh this system, a process, which infers probable diseases from clinical complications or from clinical manifestations, was revealed and confirmed.(3) A experimental development of a system which utilize clinical data stored in hospital information systemA prototype system, which monitors clinical events and tells alarming reports about results of clinical examinations stored in hospital information system. This system consists of three sub-components : the first is a rule-base system which is designed to activate a previously defined action when a certain condition is satisfied about some clinical results at a certain time, the second is a monitoring system which watches the rule-base and the third is a sub-system which extracts necessary data directory from hospital information system. A feature of this monitoring system is integrated with temporal reasoning which is able to compare two two clinical data derived from different time points.(4) HL7-based message communication system between monitoring system and hospital information systemWe tried to implement a Japanese modified version of HL7 message communication protocol which is used in U.S.This implementation is a first prctical trial in Japan. The inferring engine described above is working on UNIX workstation, and necessary information to proceed the inference is transferred from the hospital information system using this modified HL7 message communication protocol. Less