High Predictive Performance Models via Semi-Parametric Survival Regression

该项目将开发具有高预测性能的新型统计模型。当应用于帮助医生治疗病人时，这些模型允许用户包括基因或其他生物标记物来预测治疗的有效性。当应用于金融风险管理时，这些模型能够包括组织或个人的持续财务状况来预测，例如贷款违约的概率或时间。将开发创新的计算方法来拟合这些模型。与传统的预测方法相比，该方法具有更大的灵活性，同时在统计精度和偏差方面具有优势。将对来自不同领域的医疗保健数据进行广泛分析。

This project will develop novel statistical models for high prediction performance. When applied to help doctor to treat patients, these models allow the users to include gene or other biomarkers for predicting effectiveness of a treatment. When applied to risk management in finance, these models are capable to include an organization's or individual's ongoing finance status to predict, for example, the probability of or time to loan default. Innovative computational methods will be developed for fitting these models. Compared to traditional prediction method, this approach allows greater flexibility while being superior in terms of statistical accuracy and bias. Extensive analyses of healthcare data from diverse fields will be undertaken.