ONTOGENESIS AND ABERRATION OF HEART RATE VARIATION CONTROL IN RELATION TO INFLUENCING PHENOMENON IN THE HUMAN FETUS

我们总结了我们的研究，题为个体发育和心率变异控制的影响现象在人类胎儿。1.与regrd的程度，一个给定的心率与以下心率在任何胎龄，注意到“心跳延迟”从妊娠23-25周的21次心跳（平均值）线性减少到妊娠28-29周的11次心跳，这表明传导系统导向的心跳逐渐受到自主神经系统的功能控制以及可能受到成熟的延髓的调节。从妊娠期开始，“心跳延迟”无明显变化，提示胎心率变异在自主神经系统功能的控制下趋于稳定。2.胎儿胃运动节律变化存在两种不同的状态，差异有统计学意义。时间 ...更多信息 事实上，这些变化似乎集中在“活跃”和“安静”阶段，在29周的妊娠开始。这种节律性的潜在机制可能表明在中枢神经系统功能的控制下，与FSM相关的超日节律的发展。3. Werner综合征的一个病例以过早衰老为特征，明显具有潜在的生殖问题风险，如宫颈机能不全，早产，4.子痫前期患者中性粒细胞脱颗粒表现为中性粒细胞总颗粒含量减少。这表明，在先兆子痫，一个可能的修改机制存在，具体在中性粒细胞脱粒和不同的N-甲酰甲硫氨酰亮氨酰苯丙氨酸诱导的超氧化物的productionsystem.Whether或不产妇条件中描述的后两类可能有助于FHR变异仍有待进一步阐明。少

We summarized our study entitled the ontogenesis and aberration of heart rate (FHR) variation control in relation to influencing phenomenon in the human fetus.1.With regrd to the extent to which a given heart rate correlates with the following heart rate(s) at any gestational age, a linear decrement in "beat-delay" from 21 beats (mean) at 23-25 weeks to 11 beats at 28-29 weeks' gestation was noted, suggesting that the conduction system-oriented heart beat gradually comes under functional control of the autonomic nervous system as well as under possible regulation by the maturing medulla oblongata. From this point in gestation thereafter, there were no significant changes in "beat-delay", thereby implying that FHR variation becomes stabilized as a result of the control rendered by the more developed autonomic nervous system function.2.As for the rhythmic changes in fetal stomach movement (FSM), two different conditions stratified with statistical significance were present. Chronological … More ly, these changes appeared to cluster into the "active" and "quiet" phases at 29 weeks' gestation onwards. The underlying mechanism of this rhythmicity is likely to demonstrate the development of ultradian rhythm pertaining to the FSM,under control of the central nervous system function.3.A case of Werner syndrome characterized by premature aging was evident to have the potential risk of reproductive problems such as incompetent cervix, premature labor, intrauterine growth retardation and hypertensive disorder.4.The neutrophil degranulation observed in preeclampsia revealed a decrease in the total granule content retained in neutrophil. This suggests that in preeclampsia, a possible modification mechanism exists, specific in neutrophil degranulation and different from the N-formyl-methionyl-leucyl-phenylalanine-induced superoxide production system.Whether or not the maternal conditions described in the later two categories possibly contribute to FHR variation remain to be further elucidated. Less