BASIC RESEARCH ON BIOLOGICAL EFFECTS OF MAGNETIC FIELDS

本项目主要研究强静磁场对反磁水和顺磁氧行为的影响。1.磁场分离水(摩西效应)。在研究抗磁流体在8T以下的静磁场中的性质时，我们观察到较高梯度的磁场将水面向后推的现象。2.溶解氧浓度的重新分布。用溶氧仪测量了水中氧浓度的空间分布。磁场对人体外周血液循环和皮肤温度的影响。我们研究了8T静磁场对麻醉大鼠外周血流量、血压、心率和体温的影响。在磁场暴露期间，血流量减少了10%。皮肤温度下降可能是由于磁场加速了皮肤中水分的蒸发。在强磁场下，过氧化氢酶、黄嘌呤氧化酶和其他酶催化的生物化学反应。我们研究了高达14T的磁场是否会影响几种酶的活性。我们没有观察到对超氧化物歧化酶、过氧化物酶和黄嘌呤氧化酶反应的影响。然而，我们观察到过氧化氢和过氧化氢酶反应混合物在磁场暴露期间和之后的吸光度的变化。结果表明，磁场影响反应混合物中过氧化氢分解产生的氧泡的动态运动，但不影响过氧化氢酶本身的催化活性。

This project focuses on the effects of intense static magnetic fields on the behavior of diamagnetic water and paramagnetic oxygen.1.Parting of Water by Magnetic Fields ( Moses Effect). When studying the properties of diamagnetic fluids in static magnetic fields up to 8T we observed the phenomena that the surface of the water was pushed back by magnetic fields of higher gradients.2.Redistribution of Dissolved Oxygen Concentration. The spatial distribution of oxygen concentration dissolved in water was measured by a dissolved oxygen meter. A clear redistribution of oxygen concentration was observed, and the dissolved oxygen concentration increased more then 10% around the center of the magnet.3.Effect of Magnetic Fields on Peripheral Blood Circulation and Skin Temperature In Vivo. We studied the effect of 8T static magnetic fields on the peripheral blood flow, blood pressure, heart rate, and body temperature of an anesthetized rat. Blood flow decreased by 10% during magnetic field exposure. Skin temperature decreases may be attributable to the accelerated evaporation of water from the skin by magnetic fields.Biochemical Reactions Catalyzed by Catalase, Xanthine Oxidase, and Other Enzymes Under Intense Magnetic Fields. We studied whether magnetic fields of up to 14T affect the activity of several enzymes. We observed no effect on the reaction of superoxide-dismutase, peroxidase, and xanthine oxidase. However, we observed changes in the absorbance of the reaction mixture of hydrogen peroxide and catalase during and after magnetic field exposures. The results indicate that magnetic fields affect the dynamic movement of oxygen bubbles that are produced in the reaction mixture by the decomposition of hydrogen peroxide, but not the catalytic activity of the catalase itself.