Space, time and boundary conditions: Mathematics for evolving plaques.

该项目旨在创建新的数学理论来模拟导致心脏病发作和中风的动脉粥样硬化斑块的形态，随着斑块的生长或消退。该项目希望设计出新的数学工具，为斑块内的细胞过程制定新的空间模型。这些应该为斑块的生长和空间结构提供一个新的窗口。预期的结果包括强大而可靠的数学模型，了解斑块演变的新工具，以及与科学家和数学家的国内和国际合作。这将提供显著的好处，包括增加在血管生物学中使用数学模型的能力和培养跨学科方法的年轻研究人员。

This project aims to create new mathematical theory to model the morphology of atherosclerotic plaques, which cause heart attacks and strokes, as plaques grow or regress. The project expects to devise new mathematical tools for formulating novel spatial models for cellular processes inside the plaque. These should give a new window into plaque growth and spatial structures . Expected outcomes include powerful and reliable mathematical models, new tools to understand plaque evolution, and national and international collaborations with scientists and mathematicians. This should provide significant benefits including increased capacity to use mathematical models in vascular biology and training young researchers in interdisciplinary methods.