A STUDY ON THE ROLE OF HUMAN BREAST MILK IN PREVENTION OF INFBCTION -NORMAL THROAT FLORA OF BREAST FED INFANTS-

本文对30例1-2个月和2-6个月的健康婴儿进行了咽部微生物区系调查。通过革兰氏染色、形态学和血琼脂溶血类型鉴定α-溶血性链球菌、γ-链球菌、奈瑟氏菌属和葡萄球菌。肺炎链球菌、金黄色葡萄球菌、流感嗜血杆菌、卡他莫拉菌分别采用光菌素试验、凝固酶试验和API NH鉴定。（1）无论喂养方法如何，所有婴儿的第一次和第二次培养中α溶血性链球菌的发病率为100%。γ-链球菌感染率无特异性变化趋势。（2）母乳喂养婴儿奈瑟菌感染率（前12.5%、后12.5%）低于混合喂养婴儿（前50.0%、后0.0%）和配方奶粉喂养婴儿（前20.0%、后20.0%）。（3）凝固酶阳性葡萄球菌在母乳喂养的婴儿中发病率最高，提示不同喂养方式的婴儿咽喉部菌群存在差异。母乳可能有效地建立正常的咽喉微生物区系，防止致病菌的生长。

We investigated the throat rnicroflora of 30 healthy infants at the age of 1-2 months and 2-6 months. Alpha haemolytic Streptococcus, Gamma Streptococcus, Neisseria species, amd Staphylococcus were identified is by gram stain, morphology and type of haemolytis on blood agar. S.pneumonia, S.aureus, H.influenzae, M.catarrhalis were identified by optohin test, coagulase test and API NH,respectively.(1)The incidence of the Alpha haemolytic Streptococcus was 100 percent in first and second cultures of all infants regardless the method of feeding. There was not specific tendency of the incidence of Gamma Streptococcus.(2)The incidence of Neisseia species was lower in breast fed infants (first 12.5%, second 12.5%) relative to mixed-fed infants (first 50.0%, second 0.0%) and formula fed infants (first 20.0%, second 20.0%).(3)The incidence of Coagulase Positive Staphylococcus was the highest in breastfed infants.These results suggests that these are differences in the throat microflora among infants with different feeding methods. Human breast milk might be efficacious in establishing the normal throat microflora which prevents the growth of pathogenic bacteria.