The Effects of Day Treatment on Disabilities and Relapse Prevention of schizophrenia.

我们的假设是，最佳的药物治疗可以改善精神分裂症的残疾和复发率，从而使长期预后更好。我们在1996年对与我们的研究项目合作的7天治疗中心和8个社区讲习班的工作人员进行了评估培训。我们在1997年1月至1998年12月期间登记了这些设施的新服务员。现在我们对80名注册服务员进行了两年的跟踪调查。1、受试者：80名登记在册的受试者被其精神科医生诊断为精神分裂症。男性52例。平均年龄为33.8岁。平均发病年龄为24.0岁。方法：在两年内共对受试者进行4次评估，分别为：(1)治疗开始时、(2)治疗开始半年、(3)治疗开始后1年、(4)治疗开始后2年。评估方法为精神疾病患者生活评定量表（LASMI）、精神病学简易评定量表（BPRS）、WHO-QOL量表和全球评定量表（GAS）。3、结果与讨论：仅1/3的受试者完成了1年的随访研究，目前仍在继续随访研究。因此，我们报道了起始点（n=80）、半年后（n=31）和一年后（n=21）的结果。日间治疗组与社区工作坊组在人口学特征、LASMI、GAS和WHO-QOL方面无显著差异。半年后，日间治疗组LASMI耐力/稳定性量表较开始时显著改善，人际关系量表和工作量表得分显著高于社区工作坊组。LSAMI日常生活量表的改善与WHO-QOL心理量表的改善有显著的相关性。1年后，日间治疗组的LASMI日常生活量表较开始时有显著改善。我们的结论是，精神分裂症残障的某些组成部分（即稳定性和日常生活技能）可以通过日常治疗而改善，主观生活质量也会发生变化。少

Our hypothesis is that day treatment with optimal pharmacotherapy can improve disabilities and relapse rate of schizophrenia which will lead long term prognosis to be better. We had practiced training of evaluation for staff of seven day treatment centers and eight community workshops which co-operated with our research project in 1996. We registered new attendants of these facilities from January 1997 to December 1998. Now we are following 80 registered attendants for two years.1, Subjects: 80 registered attendants were diagnosed with schizophrenia by their psychiatrists. Fifty-two cases were male. The average age was 33.8 year old. The average age of onset of schizophrenia was 24.0 year old. The average umber of previous hospitalization was 1.9.2, Method: We evaluated subjects four times for two years: (1) at the start of the treatment of day treatment centers or community workshops, (2) half year from the start, (3) one year later, (4) two years later, Evaluation measures were the L … More ife Assessment Scale for persons with Mental Illness (LASMI), the Brief Psychiatric Rating Scale (BPRS), the WHO-QOL scale, and the Global Assessment Scale (GAS).3, Results and Discussion: We have finished one-year follow up study only in 1/3 subjects, and we are now continuing follow-up study. Thus we reported results at the start point (n=80), half-year later (n=31), and one-year later (n=21). There was no significant difference of demographic features, LASMI, GAS, and WHO-QOL between the day treatment group and the community workshops group. At the point of half year later, the day treatment group showed significant improvement of Endurance/Stability subscale of LASMI than at the start point, and significant better score of Interpersonal relationship subscale and Work subscale of LASMI than the community workshops group. There was significant correlation between improvement of Daily living subscale of LSAMI and improvement of psychological subscale of WHO-QOL. At the point of one year later, the day treatment group showed significant improvement of Daily living subscale of LASMI than at the start point. Our conclusion was that some components of disabilities of schizophrenia (I.e. stability and daily living skills) could be improved by day treatment with change of subjective QOL. Less