A Development of Carbon-Carbon Bond Forming Reaction without Protection of Hydroxyl Group and Carboxyl Group

本文介绍了无羟基和羧基保护的碳-碳键形成反应的研究进展：(1)三氯化铋-金属锌-烯丙基溴催化烯丙基单元格氏加成生成含羧基的羰基化合物。(2)金属铋存在下烯丙醇催化醛的烯丙化反应。(3)金属镁/三氯化铋双金属体系中醛的水相Barbier-Grignard烯丙基化反应。(4)在水相介质中，烯丙基格氏试剂和各种金属盐催化的醛的烯丙基化反应。在水介质中使用烯丙基锡化合物。(6)使用四烯丙基锡进行不对称烯丙基化合物。(7)铋催化无保护碳水化合物的烯丙化反应。

This summary presents the research results of a development of carbon-carbon bond forming reaction without protection of hydroxyl group and carboxyl group(1) A Grignard-type additon of allyl unit to carbonyl compounds containing a carboxyl group by using bismuth trichloride-metallic zinc-allyl bromide.(2) Allylation of aldehydes by using allylic alcohols in the presence of metallic bismuth(3) A novel aqueous Barbier-Grignard-type allylation of aldehydes in a metallic magnesium/bismuth trichloride bimetal system.(4) Allylation of carbonyl compounds by using allyl Grignard reagent and various metallic salts in aqueous media.(5) Allylation of aldehydes by using allyltin compounds in aqueous media.(6) Asymmetric allylation of carbonyl compounds by using tetraallyltin.(7) Bismuth mediated allylation of unprotected carbohydrates.