人体近端肾小管尿酸盐转运蛋白的分离与分析-猫眼课题宝

人体近端肾小管尿酸盐转运蛋白的分离与分析

批准号：

10671010

负责人：

ICHIDA Kimiyoshi

金额：

$1.22万

依托单位：

JIKEI UNIVERSITY SCHOOL OF MEDICINE

依托单位国家：

日本

项目类别：

Grant-in-Aid for Scientific Research (C)

财政年份：

1998

资助国家：

日本

项目状态：

已结题

起止时间：

1998 至 1999

来源：

https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-10671010/

关键词：

URATE hOAT1 TRANSPORTER 腎臓

项目摘要

项目成果

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中文摘要

翻译

methods:A hOAT1 expressing mouse proximal tubule cell line of second segment was established and used inthis study. By measuring the cellular uptaked of D114 -uratecharacteristics of urate transport via hOAT1 were clarified.Results：The Km value and The Vmax value of D114 D1C-urate transport via hOAT1 were 943±84 μM and 1286±162pmo1/mg protein/min, respectively.Conclusions：As the first cloned human urate transporter，we clarified the characteristics of urate transport via hOAT1。

英文摘要

Methods : A hOAT1 expressing mouse proximal tubule cell line of second segment was established and used in this study. By measuring the cellular uptaked of ィイD114ィエD1C-urate, characteristics of urate transport via hOAT1 were clarified.Results : The Km value and the Vmax value of ィイD114ィエD1C-urate transport via hOAT1 were 943±84 μM and 1286±162 pmo1/mg protein/min, respectively.Conclusions : As the first cloned human urate transporter, we clarified the characteristics of urate transport via hOAT1.

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