Analysis of the motor unit action potentials in patients with myofascial pain

为了比较肌筋膜痛患者和无症状对照组咀嚼肌在次极量自主收缩水平下运动直至动作电位(MUAP)的形态和放电特性，并评价肌筋膜痛在神经肌肉疾病中是否具有异常的肌电特性，我进行了以下四个实验：(1)首先，我们探索了利用每秒转数(TS)和每转幅度(AT)作为评估咀嚼肌功能的方法的可行性，结果表明，在所有收缩水平下，AT随收缩程度的增加而增加，呈线性关系。TS表现为先陡峭后平坦的非线性增长，并用三次多项式函数进行模拟。我们认为，TS和AT可能为新兵…的潜在机制提供了有价值的生理信息(2)其次，我试图证明利用肌电分解系统(ADEMG)作为一种评估口腔和咀嚼肌功能的手段的可行性，该系统位于无症状健康女性的右侧咬肌，并再次证实了高达30%MVC的ADEMG系统在人类咬肌中的有用性；(3)第三，我比较了亚最大随意收缩水平下肌肉筋膜疼痛患者和无症状对照组咬肌MUAP的形态和放电特性，并评估了在神经性肌肉疾病中，肌肉筋膜痛是否具有异常的肌电特性。因此，我未能证明MUAP有任何异常的配置属性，通常在出现神经肌肉疾病的情况下会被发现；(4)最后，我检查了患有慢性肌痛的颞下颌关节紊乱症(TMD)患者是否会增加头颈部以外偏远部位的疼痛敏感性，并评估内源性疼痛抑制系统是否在这些患者中良好地触发了缺血性疼痛的功能。因此，我猜测TMD患者在偏远部位的疼痛敏感性增加，我还提供了其他证据，表明患有慢性咀嚼肌痛的TMD患者的内源性阿片系统可能会受损。较少

To compare the configurational and firing properties of motor until action potentials (MUAPs) in the masseter muscles between myofascial pain patients and asymptomatic controls at submaximal voluntary contraction levels, and to evaluate whether myofascial pain has abnormal electromyographic properties observed in neuromuscular disorders or not, I performed the below-mentioned four experiments: (1) At first, We explored the feasibility of utilizing the turns per second (TS) and amplitude per turn (AT) in conjunction with surface electrodes as a method for assessing masticatory muscle function, and results showed that the AT increased with contraction at all contraction levels, demonstrating a linear relationship, while the TS showed a nonlinear increase characterized by an initial steep rise followed by a plateau, which was simulated with a third polynomial function. We considered that the TS and AT may provide valuable physiological information about the underlying mechanisms of recrui … More tment and the firing of motor units; (2)Second, I tried to demonstrate the feasibility of utilizing electromyographic decomposing systems (ADEMG) as a means to assess oral and masticatory muscle function using concentric needle electrodes at the right masseter muscles of asymptomatic healthy females, and we reconfirmed the usefulness of the ADEMG systems up to 30% MVC in the human masseter muscles; (3)Third, I compared the configurational and firing properties of MUAPs in the masseter muscles between myofascial pain patients and asymptomatic controls at submaximal voluntary contraction levels, and I evaluated whether myofascial pain has abnormal electromyographic properties observed in neuromuscular disorders or not. Consequently, I failed to demonstrate any abnormal configurational properties of MUAPs, frequently recognized in case of neuromuscular disorders; (4)Finally, I examined whether or not Temporomandibular Disorders (TMD) patients with chronic myalgia have increased pain sensitivity at remote sites outside of the head and neck region, and to evaluate whether endogenous pain inhibitory systems triggered ischemic pain functions favorably in those patients. As a result, I guessed that TMD patients have increased pain sensitivity at remote sites, and I also provided additional evidence that the endogenous opioid systems may become impaired in TMD patients with chronic masticatory myalgia. Less