A research of recovery of skeletal muscle paralysis using position emission tomography

[目的]应用正电子发射断层扫描（PET）分析脑卒中患者的肌肉状况。我们用18F-FDG PET方法测量了水平行走时下肢的肌肉活动。采用PET透射模式测量四肢各节段的体积和密度。[结果]1.首先，我们用18F-FDG PET方法分析了健康人在水平行走时下肢肌肉的活动。同时证明了测量下肢肌肉活动的有效性。有趣的发现是，在水平行走时，小腿肌肉的活动大于大腿肌肉。比目鱼肌的肌肉活动是所有肌肉中最大的检查。臀肌中，臀小肌的肌电活动大于臀大肌和臀中肌.脑卒中偏瘫侧小腿肌肉活动度低于正常人。患侧大腿肌肉活动与正常人一样大。患侧臀小肌肌电活动低于健康人。健侧内侧腘绳肌和胫骨后肌的肌电活动高于健侧. PET透射模式可以检测物体的密度。我们用这种方法测量了四肢各节段的体积和密度。我们证实了测量四肢各节段密度的可靠性。在中风患者中观察到上臂的密度降低。

[Purpose]We analyzed the muscular condition of stroke patients using positron emission tomography (PET). We measured the muscular activity of the lower extremities during level walking by 18F-fluoro-deoxyglucose (18F-FDG) PET method. We measured the volume and density of the segments of extremities by PET transmission mode.[Results]1. At first, we presented an analysis of the muscular activity of the lower extremities of healthy persons during level walking by 18F-FDG PET method. The concurrent validity of measuring the muscular activity of the lower extremity was demonstrated. The interesting findings were that,the activity of the lower leg muscles was larger than that of the thigh muscles during level walking. The muscular activity of the soleus was the largest among all the muscles examined. Among the gluteal muscles, the muscular activity of the gluteus minimus was larger than that of the gluteus maximus and gluteus medius.2. The muscular activities of the lower leg of the stroke paretic side were lower than those of healthy person. The muscular activities of the thigh of the paretic side were as large as those of healthy person. The muscular activity of the gluteus minimus of the paretic side was lower than that of healthy person. The muscular activities of the medial hamstrings and tibialis posterior of the non-paretic side were higher than those of the healthy person.3. The PET transmission mode can detect the density of object. We measured the volume and density of the segments of extremities by this method. We confirmed the reliability of measuring the density of the segments of extremities. A decrease in the density of the upper arm was observed in stroke patients.