Background of incremental MCV of student distance runners with prolonged endurance training

对长跑运动员的递增MCV进行了纵向研究，观察了KBC、血浆高密度脂蛋白和MCV特征的变化。然而，由于血液粘度的影响，MCV的增加是有限的。至少估计了在血管中流动和为组织或细胞提供氧气的最佳RBC和MCV。增加的MCV分为高、中、低三组。加薪幅度较小。高剂量组RBC显著降低，而中、低剂量组RBC无明显变化。尤其是低剂量组表现为RBC升高。这些增量MCV的差异取决于耐力训练前的初始RBC，高RBC组在耐力训练前的MCV增量有限。增加MCV的血液物质是血浆高密度脂蛋白，二者之间存在显著的相关性，相关系数与跑10000m的次数呈对数关系。在耐力训练中，由于LCAT(卵磷脂-胆固醇酰基转移酶)的典型升高，考虑了MCV与血浆高密度脂蛋白之间的LCAT活性。通过体外实验对影响MCV的其他直接因素进行了研究。结果表明，生物体负性因子CO2、低氧、低酸度、低温引起MCV升高，反之则导致MCV降低。根据这些结果，我们明确了MCV增加的因素和身体最佳状态的个体差异。

Incremental MCV of the distance runners was longitudinally studied with changes in KBC, plasma HDL andcharacteristics of MCV, in vitro. However, theincrease of MCV is limited, because of blood viscosity. At least the optimal RBC and MCV to flow in the vessels and to supply oxygen for the tissue or cells are estimated. The incremental MCVs were classified into three groups, high, middle and. low increases. The high incremental group showed significantly decrease of RBC, but middle and low groups did not show significant changes in RBC. In particular, the low group showed increase of RBC. These differences in incremental MCV were depended on initial RBC before endurance training; the incremental MCV is limited in high RBC group before endurance training. Blood material to increase of MCV was plasma HDL and there was significant relationship between them and the correlation coefficient had logarithmic relation toperfonnnce,10000m run. Then, LCAT (lecithin-cholesterol acyltransferase ) activity between MCV and plasma HDL is considered, because of typical increase of LCAT with endurance training. Another direct factors to influence on MCV were studied by in vitro experiment. As a results, minus factor to the living body, CO2, low oxygen, acidity, and low temperature caused increase of MCV and reverse factors caused decrease of MCV. From thjese results, we clarified factors to increase of MCV and individual differences in optimal state in the body.