Multicollector isotope mass spectrometer (MC-ICP-MS) with Triple-Quadrupol MS (3Q-ICP-MS)

同位素信息在化学、生物学、医学、地质学和环境科学的研究过程中发挥着越来越重要的作用。同时获得被调查样品中相关微量元素的信息往往会显着提高信息含量。我们与4个合作伙伴合作申请的系统是多接收器-ICP-MS和TripleQuad-ICP-MS的组合，其允许在消除干扰后同时分析同位素比率和痕量元素的浓度。样品将以液体（雾化器、色谱装置）或固体（激光消融、ETV耦合）形式引入。在未来几年中，我们将重点关注以下主题：（a）通过同位素稀释分析精确定量固体材料中的元素浓度，不确定度为± 1%/制备用于空间分辨分析的不同元素的参考材料（适用领域：（B）纯物质中同位素和微量元素的测定（W，C，Si）与ETV偶联后（c）研究生物沥滤过程中的细菌/酶调节过程（同位素系统：（4）建立了岩浆岩Hf同位素、碳酸岩Sr同位素、输沙面积分析（主微量元素和稀土元素），以及单矿物调查（磷灰石、方解石、云母、长石、石榴石、金红石、钛铁矿、锆石）（矿物化学和同位素--B、Li、Lu-Hf、Pb、Rb-Sr、U-Pb）（e）高盐浓度溶液中的同位素和微量元素分析（应用领域采矿、电池生产和回收、环境科学）（同位素系统：B、Li、S、Mg）用于调查原料的来源、生产和回收过程中工艺参数的影响，以及热力学数据库THEREDA的扩展，该数据库用于计算盐地层中正在进行的或潜在的溶解和结晶过程。(f)在应用同位素富集的起始材料（基于Fe和Mg的可吸收植入物合金;同位素系统：Mg、Fe、Gd、Nd、Ag）后，通过空间分辨分析研究植入物材料、生物体中的降解、运输和储存过程

Isotopic information plays an increasing role for the investigation of processes in chemistry, biology, medicine, geology and environmental sciences. A simultaneously obtain information about relevant trace elements in the samples under investigation often improves the information content dramatically. The system we apply for in collaboration with 4 partners is a combination of a Multicollector-ICP-MS and a TripleQuad-ICP-MS which allows for a simultaneous analysis of isotope ratios and concentrations of trace elements after elimination of interferences. Samples will be introduced either as liquids (nebulizer, chromatography unit) or solids (laser ablation, ETV-coupling). During the next years we will focus on the following topics: (a) precise quantification of element concentrations in solid materials with  1 % uncertainty by isotope dilution analysis / Preparation of reference materials wirh different elements for a spatially resolved analysis on the micro- and nanoscale (fields of application:: plant and animal tissues, new materials) (b) Isotope and trace element determination in pure substances (W, C, Si) after coupling with ETV ( method developments) (c) Investigation of bacteriologically/enzymatically regulated processes during bioleaching (Isotopic systems: S, Fe, Re, Os and other PGE) (d) Establishing of routine methods for the determination of Hf-Isotopy in Magmatits, Sr-Isotopy in Carbonatits, the sediment delivery area analysis (main and trace elements with REE), as well as the investigation of single minerals (Apatite, Calcite, Mica, Feldspar, Garnet, Rutile, Titanite, Zircon) (mineral chemistry and isotopy -B, Li, Lu-Hf, Pb, Rb-Sr, U-Pb) (e) Isotope and trace element analysis in solutions with high salt concentrations (application fields mining, battery production and recycling, environmental sciences) (Isotopy systems: B, Li, S, Mg) for the investigation of the provenance of raw materials, the influence of processing parameters during production and recycling, as well as the extension of the thermodynamic datenbase THEREDA, which is applied for calculations of ongoing or potential dissolution and crystallization processes in salt formations. (f) Investigation of implant materials, degradation-, transport- and storage processes in organisms with spatially resoved analysis and after application of isotopically enriched starting materials (resorbable implant alloys based on Fe and Mg; Isotopy systems: Mg, Fe, Gd, Nd, Ag)