Exploration for Traditional Anti-infectious Medicinal Plants in Central Africa

对中非地区传统抗感染药用植物进行了广泛的探索研究，发现了20种候选药用植物。结果表明，栀子花和黄花蒿的MeOH提取物分别具有显著的抗疟活性和杀锥虫活性。生物测定法对提取物进行分离，分离出三种类黄酮和青蒿素作为主要的生物活性成分。

Extensive exploration research for traditional anti-infectious medicinal plants in Central Africa disclosed twenty candidate medicinal plants. As a result of evaluation for in vitro antimalarial and trypanocidal activity of these collected medicinal plants, the MeOH extracts from Garcinia kola and Artemisia annua were shown to exhibit significantly potent antimalarial and trypanocidal activity, respectively.Bioassay guided separation of the extracts resulted in isolation of three biflavonoids and artemisinin as responsible bioactive principles.