Epidemiological survey on the high-risk zoonosis in the southeast asian countries

本研究旨在调查东南亚国家通过动物和食物入侵我国的高危人畜共患病的现状。狂犬病毒(1)印度尼西亚：从患狂犬病的狗脑中检测到N基因，与中国和菲律宾的分离株相似。(2)越南：在蝙蝠脑中未检出狂犬病毒N基因，但在犬血清中检出狂犬病毒中和抗体。Q热立克次体(1)泰国：从鸡和牛血清中检测到Q热抗体，从牛身上的蜱虫中检测到克希氏菌DNA。(2)印度尼西亚：从鸡和牛血清中检测到Q热抗体。(3)越南：从鸡和牛的血清中检测到Q热抗体，从鸡和牛的血清中检测到Coxiella DNA。泰国：从鸡粪中分离出大量多重耐药肠球菌。(2)印度尼西亚：从鸡粪便中分离到多种耐药肠球菌，并分离到大量耐万古霉素肠球菌（VRE）。(3)越南：从鸡和牛的粪便中分离出大量多重耐药肠球菌。由此可见，狂犬病毒、伯纳蒂克希菌和VRE等耐药菌在我国周边东南亚国家传播，存在通过动物和食品入侵我国的可能性。

This study investigates to clarify the present situation of high-risk zoonosis to invade our country through an animal and food in the southeast asian countries.1. Rabies virus(1) Indonesia : The N gene was detected from a dog brain that suffered rabies, and resembled that of isolates in China and Philippines.(2) Vietnam : The N gene was not detected from bat brain, but neutralizing antibody for rabies virus was found in dog serum.2. Q fever rickettsia(1) Thailand : An antibody for Q fever was detected from chicken and cattle serum, and detected Coxiella DNA from ticks attached to cattle.(2) Indonesia : An antibody for Q fever was detected from chicken and cattle serum.(3) Vietnam : An antibody for Q fever was detected from chicken and cattle serum, and Coxiella DNA was detected from chicken and cattle.3. Drug resistant bacteria(1) Thailand : A lot of multiple drug-resistant Enterococci were isolated from chicken feces.(2) Indonesia: Multiple drug-resistant Enterococci was isolated from chicken feces, and a lot of vancomycin resistant Enterococci (VRE) were isolated.(3) Vietnam : A lot of multiple drug-resistant Enterococci were isolated from chicken and cattle feces.From these results, rabies virus, Coxiella burnetti and drug resistant bacteria including VRE spread in the southeast asian countries which surrounded our country, and the possibility exists to invade our country through an animal and food.