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Study on Magnetic Targeting of Magnetized Medicine Droplet

Study on Magnetic Targeting of Magnetized Medicine Droplet
磁化药滴磁靶向研究
批准号:
17560160
负责人:
YAMANE Ryuichiro
金额:
$2.39万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2005
资助国家:
日本
项目状态:
已结题
起止时间:
2005 至 2007

项目摘要

项目成果

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中文摘要
翻译
磁性液体的医学应用之一是通过磁力将磁性药物靶向疾病部位。这种抗癌药物不仅能攻击癌细胞,还能攻击正常细胞,最好只将药物集中在患病部位。其中一种方法是将药物磁化或制成药物的磁性乳剂,并利用磁力将其固定在疾病部位。为此,应将磁性液滴或磁性乳剂捕获到血管的壁面上,并将其保持在防止血液流动的位置。本研究以此为基础,分别用磁性液体和水代替药物和血液,并进行了三种类型的实验。1.磁性液滴的磁性捕获:对落入水中的磁性液体液滴进行了捕获试验。根据磁力的强度,对磁性液滴的捕获分为四种类型。对捕获条件进行了检查。磁性液滴的磁性支撑:将磁性液体的液滴放置在通道的底部,并在磁力的作用下固定在水的流动的位置。针状的尖刺出现在液滴上,并随着水流向下游移动。观察和分析了扣球的运动情况。表面张力对液滴形状的影响:将不同材料覆盖在液滴表面,观察液滴的形状。
英文摘要
One of the medical applications of the magnetic fluid is to target the magnetic drug to the diseased part by means of the magnetic force. The anticancer drug attacks not only the cancer cells but also the normal ones, and it is desirable to concentrate the drug only to the diseased part. One of the methods is to magnetize the drug or to make the magnetic emulsion of the drug and to fix it to the diseased part using the magnetic force. For this purpose the magnetic droplet or the magnetic emulsion should be captured to the wall surface of the vessel and held in position against the flow of the blood. In the present research, as the basis of this problem the drug and the blood were replaced with the magnetic fluid and the water, respectively, and three types of experiments were conducted.1.Magnetic capture of magnetic droplet : Trial was conducted to capture the magnetic fluid droplet falling in the water. Capture of the magnetic droplet is classified into four types according to the strength of the magnetic force. The condition of capture is examined.2. Magnetic support of magnetic droplet : A droplet of the magnetic fluid was placed on the floor of the channel and was held in position against the flow of the water with the magnetic force. The needle-like spikes emerged on the droplet and moved downstream with the flow. The motion of the spikes was observed and analyzed.3. Effect of surface tension on shape of droplet : Surface of the droplet was covered with different materials and the shape of the spikes was observed.
期刊论文(0)
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会议论文
Fundamental Research on Magnetic Drug Targeting(in Japanese)
磁性药物靶向的基础研究(日语)
DOI: --
发表时间: 2008
期刊: Report of Kokushikan University High-Tech Research Center (in press)
影响因子: --
作者: [R., Yamane]
通讯作者: Yamane
Experimental Research oll Tribological Properties of Mn_0.78Zn_0.22Fe_2O_4Magnetic Fluid
Mn_0.78Zn_0.22Fe_2O_4磁流体摩擦学性能的实验研究
DOI: --
发表时间: 2007
期刊: 磁性流体連合講演論文集講演会講演論文集
影响因子: --
作者: [L. J. Wang, C. W. Guo, R. Yamane]
通讯作者: R. Yamane
DOI: --
发表时间: 2006
期刊: 国士舘大学ハイテクリサーチセンタ平成17年度研究報告書 (印刷中)
影响因子: --
作者: [山根隆一郎, 崎山伸彦]
通讯作者: 崎山伸彦
DOI: --
发表时间: 2007
期刊: Report of Kokushikan University High-Tech Research Center
影响因子: --
作者: [R., Yamane]
通讯作者: Yamane
共 19 条
    Study on Formation and Stability of Virtual Channel Levitated by Strong Magnetic Field
    • 批准号:
      14550159
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.3万
    • 财政年份:
      2002
    • 负责人:
      YAMANE Ryuichiro
    • 依托单位:
    Levitation and Non-Contacting Control of Liquid Flow Utilizing Mose's Effect
    • 批准号:
      10450072
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $5.63万
    • 财政年份:
      1998
    • 负责人:
      YAMANE Ryuichiro
    • 依托单位:
    Development of the bouble difusion augmentator of interface instability type by using an unsteady Lorentz force
    • 批准号:
      05555057
    • 项目类别:
      Grant-in-Aid for Developmental Scientific Research (B)
    • 资助金额:
      $5.12万
    • 财政年份:
      1993
    • 负责人:
      YAMANE Ryuichiro
    • 依托单位:
    Development of molten metal holder of Faraday type
    • 批准号:
      02555038
    • 项目类别:
      Grant-in-Aid for Developmental Scientific Research (B)
    • 资助金额:
      $2.69万
    • 财政年份:
      1990
    • 负责人:
      YAMANE Ryuichiro
    • 依托单位:
    海外基金