Early diagnosis of myocardial ischemia using magnetocardiogram
Early diagnosis of myocardial ischemia using magnetocardiogram
批准号:
18590532
负责人:
NOMURA Masahiro
金额:
$2.51万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2006
资助国家:
日本
项目状态:
已结题
起止时间:
2006 至 2007
中文摘要
我们研究了电流密度图方法是否有助于心电图检测不到的心脏电流的可视化。1)梗死向量的评估使用磁心动图记录陈旧性下壁心肌梗死(MI组)和正常健康受试者(正常组)。心脏的电动势由电流密度图估计。在心室去极化相的电流密度图中,与正常受试者不同,MI组的心室去极化相的心磁图推导出多个电流密度。在MI组的4例患者中,提示多个电流源,体表心电图未检测到。心磁图可以检测到心电图无法检测到的心肌梗塞电动势; 2)检测心电图无法检测到的心电流 ...更多信息 50例健康成人(N组),40例左室超负荷(LVO组),15例右室超负荷(RVO组),10例陈旧性下壁心肌梗塞(OMI组),30例糖尿病(DM组)。MCG记录与二阶导数超导量子干涉仪(SQUID)梯度仪使用液氦。分别制备单极心前区心电图和心磁图的等电位图和电流密度图,并检测心脏电流。心室除极相电流密度图显示N组为一个电流密度峰值。然而,在OMI组中,电流密度图显示电流密度区域的多个峰。RVO组在右上级区和左胸区检测到两个电流密度峰,这两个双极分别来自右心室和左心室衍生的心脏电流。此外,右心室电流密度的大小与肺动脉收缩压之间存在显著相关性。N组在心室复极相的电流密度图仅显示单一电流源。然而,异常的电流源的电流密度图中频繁检测到,即使在患者显示没有异常的等电位图在LVO,DM,和OMI groups.Our结果表明,MCG与电流密度图是有用的检测心脏电流检测心电图检测不到的早期阶段。少
英文摘要
We investigated the issue of whether the current density map method, in which cardiac current is estimated from the magnetic gradient, facilitates the visualization of cardiac current undetectable by ECG.1) Evaluation of an infarction vectorOld inferior myocardial infarctions (MI group) and normal healthy subjects (Normal group) were recorded using magnetocardiometer. The electromotive force of the heart was estimated from a current density map. In the current density map of the ventricular depolarization phase, multiple current densities were deduced from magnetocardiograms of the ventricular depolarization phase in the MI group, unlike normal subjects. In 4 patients in the MI group, multiple current sources were suggested, which were not detected in a body surface electrocardiogram. Magnetocardiogram is capable of permitting infarct electromotive forces to be detected, which could not be deduced from electrocardiography data.2) Detection of cardiac current undetectable by electrocard … More iography using magnetocardiography in various cardiac diseasesThe subjects were 50 healthy adults (N group), 40 patients with left ventricular overloading (LVO group), 15 patients with right ventricular overloading (RVO group), 10 patients with an old inferior myocardial infarction (OMI group), and 30 patients with diabetes mellitus (DM group). MCGs were recorded with a second derivative superconducting quantum interference device (SQUID) gradiometer using liquid helium. Isopotential maps and current density maps from unipolar precordial ECG leads and MCGs, respectively, were prepared, and the cardiac electric current was examined. The current density map at the ventricular depolarization phase showed one peak of current density in the N group. However, in the OMI group, the current density map showed multiple peaks of current density areas. In the RVO group, two peaks of current densities were detected at the right superior region and left thoracic region and these two diploles appeared to be from the right and left ventricular derived cardiac currents, respectively. Moreover, there was a significant correlation between the magnitude of the current density from the right ventricle and the systolic pulmonary arterial pressure. The current density map at the ventricular repolarization phase in the N group showed only a single current source. However, abnormal current sources in the current density maps were frequently detected even in patients showing no abnormalities on isopotential maps in the LVO, DM, and OMI groups.Our results suggest that MCG with a current density map is useful for detecting cardiac current undetectable by ECG in an early stage. Less
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臨床医からみた不整脈診断のシンポと問題点
临床医生视角下心律失常诊断研讨会及问题
DOI:
--
发表时间:
2007
期刊:
日本生体磁気学会誌 20巻1号
影响因子:
--
作者:
[野村 昌弘, 他]
通讯作者:
他
Evaluation of an infarction vector by magnetocardiogram : detection of electromotive forces that cannot be deduced from an electrocardiogram
通过心磁图评估梗塞向量:检测无法从心电图推断出的电动势
DOI:
--
发表时间:
2007
期刊:
International congress Series 1300
影响因子:
--
作者:
[Nomura, M]
通讯作者:
M
臨床医からみた不整脈診断の進歩と問題点
临床医生视角下心律失常诊断的进展与问题
DOI:
--
发表时间:
2007
期刊:
日本生体磁気学会誌 20巻1号
影响因子:
--
作者:
[Koizumi KT., et. al., Koizumi Y.K. et al., Nomura M, 野村昌弘]
通讯作者:
野村昌弘
Evaluation of pulmonary arterial pressure using current density map in patients with right ventricular overloading
使用电流密度图评估右心室超负荷患者的肺动脉压
DOI:
--
发表时间:
2006
期刊:
The Journal of Japan Biomagnetism and Bioelectromagnetics Society 19(1)
影响因子:
--
作者:
[Nomura, M]
通讯作者:
M
Evaluation of an infarction vector by magnetocardiogram: detection of electromotive forces that cannot be deduced from an electrocardiogram
通过心磁图评估梗塞向量:检测无法从心电图推断出的电动势
DOI:
--
发表时间:
2007
期刊:
International congress Series 1300
影响因子:
--
作者:
[Koizumi KT., et. al., Koizumi Y.K. et al., Nomura M, 野村昌弘, Nomura M]
通讯作者:
Nomura M
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Clinical application of magnetocardiogram by a high temperature superconducting quantum interference device
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负责人:NOMURA Masahiro
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依托单位:
Recording of biomagnetic fields, especially magnetocardiogram and magnetogastrogram, using a high-temperature (-196゚C) superconducting quantum interference device
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