Analysis of mechanisms underlying maintenance of plant stem cells

在本研究中，我们将重点研究细胞分裂的负调控因子，以揭示植物干细胞维持的分子机制。研究发现，茎尖表皮产生的长链脂肪酸产生的信号作用于内细胞层抑制干细胞分裂。此外，我们利用CDT1a的羧基末端区域开发了一个新的S期特异性报告基因来监测分生组织中的细胞增殖。

In this study, we focused on negative regulators of cell division to reveal molecular mechanisms underlying maintenance of plant stem cells. We found that some signal derived from very long chain fatty acid, which is produced in the epidermis of shoot apices, acts on inner cell layers to suppress stem cell division. Moreover, we developed a novel S phase-specific reporter gene by using the carboxy-terminal region of CDT1a to monitor cell proliferation in meristems.