Chemical Biology of Golgi Membrane Dynamics
Chemical Biology of Golgi Membrane Dynamics
批准号:
19580098
负责人:
TAKATSUKI Akira
金额:
$2.91万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2009
中文摘要
高尔基体以动态平衡的方式维持其特有的结构,但其机制尚不清楚。影响高尔基体膜动力学的化学物质在已知影响细胞周期向有丝分裂期过渡和诱导细胞凋亡的化学物质中的比例相对较高。结果表明,它们作用于中心体,表明中心体在控制高尔基体膜动力学中起重要作用。
英文摘要
The Golgi maintains its characteristic structure by a dynamic equilibrium manner, but this mechanism remains to be clarified. Chemicals affecting Golgi membrane dynamics were found at a relatively high ratio among those known to affect transition to mitotic phase of cell cycle and induce apoptosis. Results indicating that they act on the centrosome suggest that the centrosome plays important roles in the control of Golgi membrane dynamics.
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会议论文
Analysis of intracellular translocation of glycoproteins using inhibitors as probes
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批准号:02660108
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.34万
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财政年份:1990
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负责人:TAKATSUKI Akira
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依托单位:
Isolation and analysis of mode of action of novel inhibitors of intracellular translocation of glycoproteins
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批准号:63560099
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.28万
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财政年份:1988
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负责人:TAKATSUKI Akira
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依托单位:
海外基金