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Molecular mechanisms of various side effects of volatile anesthetics

Molecular mechanisms of various side effects of volatile anesthetics
挥发性麻醉药各种副作用的分子机制
批准号:
19591792
负责人:
MIYAMOTO Yoshikazu
金额:
$2.91万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2009

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中文摘要
翻译
通过体外运动试验,我们测定了吸入麻醉剂七氟醚和异氟醚对微管驱动蛋白运动的直接影响。应用吸入麻醉剂后,大部分微管停止滑动运动,在清除麻醉剂后,其运动能力几乎恢复。
英文摘要
By using in vitro motility assay, we determined the direct effects of inhalational anesthetics sevoflurane and isoflurane on microtubule-based kinesin motility. By applying inhalational anesthetics, most of the microtubules stopped sliding movements, and their motility almost recovered after washing out of the anesthetics.
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会议论文
Molecular mechanisms of volatile anesthetics toxicity on the immature mamarian brain cells: Analysis by single fluorescent molecule imaging.
  • 批准号:
    22591707
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $3.0万
  • 财政年份:
    2010
  • 负责人:
    MIYAMOTO Yoshikazu
  • 依托单位:
海外基金