课题基金 / 基金详情

Investigation of Inhibitory effect of Extra-Intestinal Pathogenic Escherichia coli against human neutrophils

Investigation of Inhibitory effect of Extra-Intestinal Pathogenic Escherichia coli against human neutrophils
肠外致病性大肠杆菌对人中性粒细胞抑制作用的研究
批准号:
20590463
负责人:
OHNISHI Makoto
金额:
$3.08万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010

项目摘要

项目成果

OHNISHI Makoto的其他基金

相似基金

相关文献

中文摘要
翻译
探讨了肠外致病性大肠埃希菌的分子机制。菌株CK17是UPEC O2,对血清处理表现出极高的抵抗力,对人中性粒细胞吞噬也表现出抗药性。K1胶囊对PMN耐药,但与血清耐药无关。C3分子和免疫球蛋白不能与产生K1的CK17结合。K1非依赖性血清耐药的机制仍未解决。
英文摘要
Molecular mechanism of Extra-Intestinal pathogenic Escherichia coli was investigated. The strain CK17, which is UPEC O2, showed extra high resistant to serum treatment and also resistant to human neutrophils phagocytosis. K1 capsule was responsible to PMN resistant, but not serum resistance. C3 molecule and IgG could not bind K1-produceing CK17. The mechanism of K1-independent serum resistant remains unsolved.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
腸管外病原性大腸菌の好中球食菌作用抵抗性
肠外致病性大肠杆菌的中性粒细胞吞噬抵抗
DOI: --
发表时间: 2009
期刊:
影响因子: --
作者: [大西真, 阿戸学, 志牟田健, 渡邉治雄]
通讯作者: 渡邉治雄
Analysis of commensal neisserial species as a genetic pool for drug resistant genes
  • 批准号:
    24659720
  • 项目类别:
    Grant-in-Aid for Challenging Exploratory Research
  • 资助金额:
    $2.41万
  • 财政年份:
    2012
  • 负责人:
    OHNISHI Makoto
  • 依托单位:
Model for evaluation of pathogenicity of extra-intestinal pathogenic Escherichia coli
  • 批准号:
    18590442
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $2.5万
  • 财政年份:
    2006
  • 负责人:
    OHNISHI Makoto
  • 依托单位:
海外基金