Analysis of chondroitin proteoglycans and related molecules involved in cell division control

软骨素蛋白多糖参与细胞分裂。我们使用模式生物秀丽线虫分析了软骨素蛋白多糖和相关分子，发现如下。1)线虫卵壳和渗透屏障的正确组装需要两个软骨素蛋白多糖。2)软骨素在线虫胚系减数分裂中起重要作用。3)在卵子发生过程中，软骨素蛋白多糖参与受体介导的卵黄蛋白原转运。这些发现表明，软骨素及其相关分子参与了细胞分裂控制和分子运输系统。

Chondroitin proteoglycans are involved in cell division. We analysed chondroitin proteoglycans and related molecules using model organism C. elegans and found following. 1) Two chondroitin proteoglycans are required for proper assembly of the C. elegans eggshell and osmotic barriear. 2) Chondroitin plays an important role on meiosis in nematode germ line. 3) Chondroitin proteoglycans are imvolved in receptor-mediated transport of vitellogenin during oogenesis. These findings suggest that chondroitin and related molecules are involved in cell division control and molecular transport systems.