Cohort study and preventive approach for knee osteoarthrits and anterior cruciate ligament injury

Iwaki健康促进项目显示，膝关节骨关节炎的危险因素是年龄、女性、肥胖和代谢综合征。此外，膝关节疼痛会引起运动综合征。血清透明质酸是膝关节骨关节炎的生物标志物，其升高可预测膝关节骨关节炎的进展。血清透明质酸水平较高的患者，运动疗法治疗膝关节骨性关节炎的效果较差。外翻对准是前交叉韧带损伤的危险因素。在青春期，女性外翻排列比男性大，外翻排列的角度随着年龄的增长而增大。相反，躯干稳定性的预防性训练方法（10分钟训练，每周4次）是有效的。着陆时，躯干弯曲角度增大，外翻力矩减小，躯干侧向失稳减小。青春期躯干稳定训练具有预防前交叉韧带损伤的潜力。

Iwaki Health Promotion Project revealed that the risk factors for knee osteoarthritis were aging, female, obesity, and metabolic syndrome. Furthermore, the presence of knee pain causes locomotive syndrome. Serum hyaluronan is a biomarker for knee osteoarthritis, and its elevation predicted progression of knee osteoarthritis. Also, effect of exercise therapy for knee osteoarthritis was less in those with higher serum hyaluronan.Valgus alignment was risk for ACL injury. In pubertal, valgus alignment of females is larger than males, and its angle become progressed with aging. On the contrary, preventive training approach for trunk stability (10 minutes training, 4 times a week) was effective. At landing, trunk bending angle increased, valgus moment decreased and trunk lateral instability decreased. Trunk stabilizing training for pubertal age has potential to prevent ACL injury.