Regulation of lipid composition of breast milk during lactation

母乳喂养的营养是最适合人类婴儿的所有可用牛奶。人乳含有分泌型伊加抗体、溶菌酶和乳糖苷酶，它们提供胃肠道免疫。母乳中的矿物质、蛋白质和脂肪等成分在哺乳过程中发生变化，但其变化规律尚不清楚。本研究中，核受体超家族之一的肝X受体配体（LXR）可能影响母乳脂质含量。这一结果表明，包括核受体在内的转录因子可能与哺乳期母乳成分有关。

Nutrition of breast-feeding is the most appropriate of all available milks for human infants. Human milk contains secretary IgA antibodies, lysozyme, and lactofarin, which provide gastrointestinal immunity. The composition of breast milk including minerals, prorotein and fats is changed during laction, however, the regulation of them have remained to be elucidated. In the study, the ligand of liver X receptor(LXR), one of nuclear receptor superfamily may affect the lipid contents of breast milk. This result The transcriptional factors including nuclear receptors may involve components of breast milk during lactation.