The cause and effect relationship between the intractable dermatosis by metal allergy and the metal restoration in the oral cavity.

本研究的目的是阐明金属过敏的致病机制，并建立一种新的检查方法。对患有牙齿金属过敏的顽固性皮肤病的受试者的汗液进行分析，将手浸泡在42℃温水中10分钟，提取汗液。用电感耦合等离子体发射光谱仪对样品进行了定性分析，虽然通过简单的检测检测出了16种金属元素，但在条件苛刻的情况下无法检测。有必要提高样品的调整，或分析设备的检测限。

The purpose of this study is the elucidation of a pathogenic mechanism of metal allergy and establishment of a new inspection method, when the sweat from subject who had intractable dermatosis by dental metal allergy is analyzed.The hand was soaked for 10 minutes into 42℃warm water, and sweat was extracted. Qualitative analysis of the sample was conducted with Inductively coupled plasma optical emission spectrometry equipment.When conditions were made severe, it became impossible to detect, although 16 kinds of metallic elements have detected by the simple examination. It is necessary to raise adjustment of the sample, or the detection limit of analysis equipment.