Elucidated of environmental and genetic effects on the neural network disorders.

在这项研究中，我们阐明了环境和遗传线索对神经网络形成的影响。首先，利用神经祖细胞分析环境应激的反应。这些作用和相关的信号转录对神经祖细胞的影响明显促进了细胞周期和神经元拉伸形状的恢复。它可能涉及神经祖细胞的生存反应，该细胞表达神经元生长因子受体，并显示对几种环境线索负责。有趣的是，神经元损伤的成年大鼠脑显示出类似的形态学改变，在非兴奋状态下促进突触前膜和突触后膜的自分泌样和自分泌样形成。

In this study, we elucidated the effects of environmental and genetic cues for the neural network formations. First, to clarify the response of environmental stress were analyzed using neuronal progenitor cells. Those effects and related signal transcription on neuro-progenitor cells were clearly promoted rescue on cell cycle and neuronal stretched shapes. It may have been involving survival response in neuro progenitor cell that was expressing the receptor of neuronal growth factors and that shown responsible for several environment cues. Interestingly, neuronal injured adult rat brain indicated similar morphological alteration that has promoted the autocrine-like and diacrine-like formation at pre- and post- synaptic membrane during a non-excitable condition.