Technical developments for high S/N ratio of diffraction data in low energy SAD phasing

在本项目中，进行了低能量SAD相位法测量衍射数据中微弱异常信号的技术开发。为了减小样品周围的x射线吸收效应，研制了氦气冷冻流系统和氦气替代室。此外，还开发了一套能快速评估衍射数据中异常信号水平的自动数据处理系统。

In this project, technical developments to measure weak anomalous signals in diffraction data for low energy SAD phasing method has been carried out. As results, a helium gas cryo-stream system and a helium gas substitution chamber has been made to decrease X-ray absorption effects around samples. In addition, automated data processing system which rapidly evaluates a level of anomalous signals in diffraction data has been developed.