Experimental research of immunological tolerance in allograft from cadaveric donors for clinical trial

在研究期间，在恒河猴身上发现，抗人胸腺细胞球蛋白可以减少T细胞的数量，可以检测到外周血单个核细胞(PMBC)的嵌合体，可以通过灌流技术进行骨髓移植。尽管没有观察到PBMC的嵌合体，但与第三方猴子的淋巴细胞相比，对供体淋巴细胞的混合淋巴细胞反应(MLR)显著减少

During the study period, it was revealed in Rhesus monkeys that anti-human thymocyte globulin may reduce the number of T-cell, that chimerism of peripheral blood mononuclear cells (PMBC) can be detected and that bone marrow transplant can be done by perfusion technique. Although chimerism of PBMC was not observed, mixed lymphocyte reaction (MLR) against the donor lymphocytes was significantly reduced compared to that against lymphocytes of third party monkey