Clinical application of preload stress echocardiography with leg-positive pressure in patients with chronic heart failure

对轻度心力衰竭患者应用下肢正压（LPP）进行负荷前负荷超声心动图。根据二尖瓣血流速度模式将患者分为3组：静息时限制性或异常（PN）、静息时和LPP期间舒张受损（IR）（稳定IR）和静息时IR和LPP期间PN（不稳定IR）。不稳定型IR的全因心脏事件发生率高于稳定型IR，PN组与稳定型IR相似。不稳定型IR患者的无事件生存率低于稳定型IR患者。负荷超声心动图负荷试验提供了除常规超声心动图参数外的轻度心力衰竭患者的其他预后信息。

Preload stress echocardiography was applied with leg-positive pressure (LPP) in patients with mild heart failure. Patients were classified into 3 groups based on transmitral flow velocity pattern: restrictive or pseudontrmal (PN) at rest, impaired relaxation (IR) at rest and during LPP (stable IR), and IR at rest and PN during LPP (unstable IR). All-cause cardiac event rate was higher in unstable IR than in stable IR, and was similar in PN group. Event-free survival was lower in unstable IR than stable IR. Preload stress echocardiography provides additional prognostic information in mild heart failure patients beyond conventional echocardiographic parameters.