Analysis of gene transcription start regulatory mechanism by crosstalk between histone modifications
Analysis of gene transcription start regulatory mechanism by crosstalk between histone modifications
批准号:
22570173
负责人:
NAKAGAWA Takeya
金额:
$2.91万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012
中文摘要
在本研究中,我研究了转录调控机制之间的串扰两个组蛋白修饰。我们已经揭示了H2AK119的泛素化和H3K4的甲基化之间的串扰。在这项研究中,我们得到了一个结果,表明参与hisotne H4乙酰化这种串扰。
英文摘要
In the present study, I investigated mechanism of transcriptional regulation by crosstalk between two histone modifications. We have already revealed the crosstalk between ubiquitylation of H2AK119 and methylation of H3K4. In this study ,we obtained a result that indicate the involvement of hisotne H4 acetylation to this crosstalk.
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会议论文
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依托单位:
海外基金