Studies on the regulatory mechanism of dispensable amino acids metabolism in response to protein requirement

这表明蛋氨酸对蛋白质营养起着信号作用，并调节蛋白质营养应答的氨基酸合成酶的表达。为了适应不同的蛋白质营养，必须有连续的营养信号。此外，酶的表达对蛋白质营养的适应性反应在各个器官中是不同的，这表明不同器官对必需氨基酸的需求不同。

It is suggested that methionine play a signal for protein nutrition and regulates the expression of enzymes of dispensable amino acids synthesis in response to protein nutrition. To adapt for different protein nutrition, consecutive nutritional signal must be required. In addition, the adaptative response of the expression of enzymes to protein nutrition is different in respective organs, suggesting that requirement of dispensable amino acids differ from organ to organ.