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Identification of MicroRNAs involved in formation of foam cells that are associated with atherosclerosis-related gene lymphotoxin-alpha

Identification of MicroRNAs involved in formation of foam cells that are associated with atherosclerosis-related gene lymphotoxin-alpha
鉴定参与与动脉粥样硬化相关基因淋巴毒素-α相关的泡沫细胞形成的MicroRNA
批准号:
22590827
负责人:
SAKATA Yasuhiko
金额:
$3.0万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012

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中文摘要
翻译
我们试图鉴定与动脉粥样硬化相关基因淋巴毒素-α(LTA)相关的泡沫细胞形成过程中涉及的microRNAs。然而,我们发现LTA不太可能参与泡沫细胞的形成。因此,我们改变了我们的计划,确定了与急性心肌梗死患者心源性死亡相关的microRNAs,急性心肌梗死是动脉粥样硬化性疾病导致死亡的主要原因。
英文摘要
We tried to Identify microRNAs involved in f ormation of foam cells that are associated with atherosclerosis-related gene lymphotoxin-alpha (LTA). However, we found that LTA was unlikely involved in foam cell formation. Thus, we changed our plan and identified microRNAs that are associated with cardiac death in patients who survived acute myocardial infarction, a major cause of death as a result of atherosclerotic diseases.
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会议论文
Circulating MicroRNAs as Therepeutic Targets for Cardiac Remodeling and Heart Failure in Patients after Acute Myocardial Infarction.
循环 MicroRNA 作为急性心肌梗死后患者心脏重塑和心力衰竭的治疗靶点。
DOI: --
发表时间: 2013
期刊:
影响因子: --
作者: [Sen Matsumoto, Yasuhiko Sakata, Daisaku Nakatani, Shinichiro Suna, Masaya Usami, Masahiko Hara, Yukio Kawahara, Toru Oka, Seiji Takashima, Tatsuya Sasaki, Hiroshi Sato, Shinsuke Nanto, Issei Komuro]
通讯作者: Issei Komuro
DOI: --
发表时间: 2012
期刊:
影响因子: --
作者: [Yusuke Kurogane, Yoshiyuki Rikitake, et al., Sen Matsumoto]
通讯作者: Sen Matsumoto
Elucidation of the mechanism of cell adhesion mediated by myocardialinfarction related gene lymphotoxin alpha
  • 批准号:
    19590816
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $3.0万
  • 财政年份:
    2007
  • 负责人:
    SAKATA Yasuhiko
  • 依托单位:
海外基金