Development of transmission-type surface plasmon resonance sensorusing nano array structures

提出了一种利用纳米阵列结构制作纳米阵列结构和透射型表面等离子体共振（SPR）传感器的新方法。采用纳米微珠自组装的方法制备了纳米阵列结构。该方法在成本和批量生产方面都优于其他电子束制造方法。虽然所研制的SPR传感器存在灵敏度和再现性方面的问题，但与其他基于Kretschmann结构和光栅耦合的SPR传感器相比，所研制的SPR传感器具有光学结构非常简单和设备小型化的优点。由于光学系统的定位也很容易，因此本研究开发的SPR传感器可用于cd型微流控装置的SPR测量。

A novel method to fabricate a nano array structure and a transmission-type surface plasmon resonance (SPR) sensor using the nano array structures were developed. The nano array structure was fabricated by self-assembly of nano beads. The fabrication method is superior to other method using electron beam in cost and mass production. Although the developed SPR sensor has problems with sensitivity and reproducibility, compared to other SPR sensor based on Kretschmann configuration and grating coupling, the developed SPR sensor has advantages that the optical configuration is very simple and the miniaturization of the equipment is possible. Since the positioning of the optical system is also easy, the SPR sensor developed in this study would be useful for SPR measurement on a CD-type microfluidic device.