Development of Environmentally Benign Selective Oxidation Reactions Using Designer Hypervalent Iodine Catalysts

在这项研究中，我们实现了几个氧化反应，使用设计的高价碘催化剂。我们已经开发了第一个例子的有机碘（V）催化的区域选择性氧化苯酚邻醌使用2-碘氧基苯磺酸（IBS）。此外，我们成功地在构象灵活的碘代芳烃的二级非键相互作用的基础上作为手性催化剂的对映选择性氧化脱芳构化的1-萘酚的合理设计。此外，我们还开发了以过氧化氢或TBHP为环境友好氧化剂，原位生成的亚（次）碘酸铵催化的羰基化合物的分子内和分子间直接x-氧酰化反应

In this study, we achieved several oxidation reactions using designer hypervalent iodine catalysts. We have developed the first example of the organoiodine(V)-catalyzed regioselective oxidation of phenols to ortho-quinones using 2-iodoxybenzenesulfonic acid (IBS). Moreover, we succeeded in the rational design of conformationally flexible iodosylarenes based on secondary nonbonding interactions as chiral catalysts for the enantioselective oxidative dearomatization of 1-naphthols. Furthermore, we have developed the intra- and intermolecular direct x-oxyacylation reactions of carbonyl compounds catalyzed by in situ-generated ammonium (hypo)iodite species with hydrogen peroxide or TBHP as an environmentally benign oxidant