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Analysis on mechanisms that enable cone photoreceptor cells to work under continuous light conditions.

Analysis on mechanisms that enable cone photoreceptor cells to work under continuous light conditions.
分析锥体感光细胞在连续光照条件下工作的机制。
批准号:
22770150
负责人:
TACHIBANAKI Shuji
金额:
$2.75万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2011

项目摘要

项目成果

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中文摘要
翻译
在脊椎动物的视网膜上,有两种类型的视觉感光细胞,称为视杆细胞和视锥细胞。视杆细胞调节夜间视觉,视锥细胞调节白天视觉。这是众所周知的锥体。视杆细胞调节夜间视觉,视锥细胞调节白天视觉。众所周知,视锥细胞持续接受光刺激的明亮条件。在本研究中,我们发现,在视锥细胞中,(1)磷酸化对视觉色素失活的效率被强烈调节,(2)磷酸化的视觉色素被迅速去磷酸化。这些机制似乎使锥细胞在明亮的条件下产生反应。
英文摘要
In vertebrate retina, there are two types of visual photoreceptor cells, called rods and cones. Rods mediate night vision, and cones mediate daytime vision. It is well known cones. Rods mediate night vision, and cones mediate daytime vision. It is well known bright conditions where cones receive light stimuli continuously. In this study, we found that, in cones,(1) the efficiency of the inactivation of visual pigments by phosphorylation is strongly modulated, and(2) phosphorylated visual pigments are dephosphorylated rapidly. These mechanisms seem to enable cones to generate responses under bright conditions.
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会议论文
錐体・桿体視細胞の応答様式を決める分子メカニズム
决定视锥细胞和视杆细胞感光细胞反应模式的分子机制
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [Daisuke Arinobu, Shuji Tachibanaki, and Satoru Kawamura, 橘木修志, 山岡弘美・橘木修志・河村悟, 金城玲, 金城玲, 橘木修志]
通讯作者: 橘木修志
桿体・錐体での視物質の脱リン酸化活性の比較と解析
视杆细胞和视锥细胞视觉物质去磷酸化活性的比较与分析
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [Daisuke Arinobu, Shuji Tachibanaki, and Satoru Kawamura, 橘木修志, 山岡弘美・橘木修志・河村悟]
通讯作者: 山岡弘美・橘木修志・河村悟
DOI: 10.1111/j.1471-4159.2010.06925.x
发表时间: 2010-10-01
期刊: JOURNAL OF NEUROCHEMISTRY
影响因子: 4.7
作者: [Arinobu, Daisuke, Tachibanaki, Shuji, Kawamura, Satoru]
通讯作者: Kawamura, Satoru
錐体視細胞における低いトランスデューシン活性化効率
视锥细胞感光器中转导蛋白激活效率低
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [Daisuke Arinobu, Shuji Tachibanaki, and Satoru Kawamura, 橘木修志]
通讯作者: 橘木修志
Analysis of the effects of the differences in lipid and protein compositions in the outer segments of cone and rod photoreceptor cells on light responses.
  • 批准号:
    16K07438
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $3.16万
  • 财政年份:
    2016
  • 负责人:
    TACHIBANAKI Shuji
  • 依托单位:
Analysis on molecular environments that bring cell-specific photoresponses to rod and cone photoreceptors.
  • 批准号:
    24570085
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $3.58万
  • 财政年份:
    2012
  • 负责人:
    TACHIBANAKI Shuji
  • 依托单位:
Analysis on the molecular mechanisms of wider dynamic range and higher time-resolution in cone photoreceptor cells.
  • 批准号:
    20700350
  • 项目类别:
    Grant-in-Aid for Young Scientists (B)
  • 资助金额:
    $2.75万
  • 财政年份:
    2008
  • 负责人:
    TACHIBANAKI Shuji
  • 依托单位:
海外基金