Regenerated cartilage differentiation evaluation method using diffusion weighted MR imaging

对于软骨组织，无创评价其分化程度、组织成熟程度、钙化程度或三维结构的进一步精细化是困难的。运动受到复杂的细胞外基质和细胞膜的限制，占关节软骨质量70-80%的水分子表现出多-多方向的扩散成分。为了了解软骨的材料特性和组织水分子的运动性之间的关系，扩散加权MR成像中的表观扩散系数是有用的。利用几种恶性肿瘤的弥散加权成像，研究了周围组织的灌注行为对弥散行为的影响。

The cartilage tissue, non-invasive evaluation their differentiation, the degree of tissue maturation, or three-dimensional structure of calcification further fine is difficult. The motion is limited by complex extracellular matrix and cell membrane, water molecules that make up 70-80% of the mass of the articular cartilage shows the diffuse component of multiple-multidirectional. In order to understand the relationship between the material properties of the cartilage and motility in the tissue water molecules, the apparent diffusion coefficient in the diffusion-weighted MR imaging is useful. Relates perfusion behavior of the surrounding tissue that would affect the diffusion behavior, using a diffusion weighted imaging obtained from several malignant tumors, presented to study the relationship.