Longitudinal study for postpartum depression(PPD): establishment of collaborative community system for the early detection and intervention of PPD

背景：据报道，产后抑郁症(PPD)在全球普通人群中的患病率为10%至15%。然而，产妇的年龄与产后抑郁的发生之间的相关性还没有很好的文献记录。为了解决这一问题，我们使用滨松母亲和儿童出生队列(HBC)估计了特定年龄段PPD的3个月累积发病率。方法：使用正在进行的出生队列研究，我们连续招募了723名怀孕中期并预计在两个研究地点之一分娩的产妇。产后抑郁分为产后3个月爱丁堡产后抑郁量表评分9分及以上者。结果：在675例产妇中，产后3个月内产后抑郁累计发生率为14.8%。年龄别估计为：25岁20.8%，25-29岁14.2%，30-34岁11.5%，≧35岁17.9%。在Logistic回归分析中，年龄为35岁的产妇发生产后抑郁的OR为1.7，在控制了伴侣年龄、产次和家庭收入后仍显著。限制：虽然样本具有代表性，但样本量适中。结论：产后抑郁的累积发病率在不同年龄段之间存在显著差异，高龄组的估计值最高。产后抑郁的累积发病率在≧为35岁的产妇中有一个高峰，然而，伴侣的年龄、产次或家庭年收入没有考虑到这一增加的估计。

BACKGROUND : The prevalence of postpartum depression(PPD) in the general population has been reported to be 10% to 15% worldwide. However, the relevance of age of the parturients to the emergence of PPD has not been well documented. To address this, we estimated the age-specific 3-month cumulative incidence of PPD using the Hamamatsu Birth Cohort for Mothers and Children(HBC).METHODS : Using an ongoing birth cohort study, we consecutively enrolled parturients who were at mid-pregnancy(n=723) and were expected to give birth at either of our two research sites. Women with PPD were defined as those scoring 9 points or higher using the Edinburgh Postnatal Depression Scale 3 months after childbirth.RESULTS : Among 675 participating parturients, 100 women were found to have PPD ; the cumulative incidence of PPD over the 3 months after childbirth was 14. 8%. The age-specific estimates were 20. 8% for<25 years, 14. 2% for 25 to 29 years, 11. 5% for 30 to 34 years, and 17. 9% for.≧35 years. In the logistic regression analysis, the increased OR for having PPD among parturients aged≧35 years was 1. 7, which remained significant after controlling for age of partner, parity, and household income.LIMITATIONS : Although the sample was representative, the sample size was modest.CONCLUSION : The cumulative incidence of PPD was significantly different across age groups, with the highest estimates in the advanced age band. There was a peak of cumulative incidence of PPD among parturients aged≧35 years, however, the heightened estimate was not accounted for by the age of the partner, parity, or annual household income.