The clinical analysis of antithrombotic and antiatherosclerotic effects of therapeutic exercise in metabolic syndrome and cerebral infarction

动脉粥样硬化引起血小板活化、内皮功能障碍和凝血纤溶障碍，导致血栓形成。此外，在缺血性病变中产生多种细胞因子并观察到细胞凋亡，导致神经元死亡扩大。本研究的目的是确定持续运动对预防动脉粥样硬化和神经元缺血性死亡的影响。在脑梗死患者中，治疗性运动可降低内皮功能障碍、血小板活化、增加纤维蛋白溶解能力、降低缺血相关细胞因子和凋亡参数。提示治疗性运动具有脑梗死二级预防和脑缺血级联抑制的作用。

Atherosclerosis causes platelet activation, endothelial dysfunction and coagulation fibrinolytic disorder, resulting in thrombosis. Furthermore, various cytokines were produced and apoptosis is observed in the ischemic lesions, resulting in the expansion of neuronal death. The aim of this study is to determine the effect of continuing exercise on the prevention of atherosclerosis and neuronal ischemic death. Therapeutic exercise decreased endothelial dysfunction, platelet activation, increased fibrinolytic capacity, and decreased ischemia-related cytokines and apoptotic parameters in patients with cerebral infarction. It is suggested that therapeutic exercise has a role in secondary prevention for cerebral infarction and inhibition of ischemic cascade.