Exhaustive analysis about the onset etiology of the pediatric inflammatory diseases by using the proteome method

本研究采用蛋白质组学方法，即综合蛋白质分析方法，对高细胞分裂血症患者急性期和恢复期的血清蛋白进行分析。(1)炎症的机制-寻找细胞因子风暴的原因-最后，我们可以在各种炎症疾病中识别出本研究中的原始蛋白，我们正在计划增加标本数量并进行添加试验。(2)炎性细胞因子的作用与“细胞因子风暴”患者的病情：分析了炎性细胞因子的各种蛋白表达、作用机制，完成了对通用蛋白的鉴定（已提交英文期刊）。(3)细胞因子风暴将在儿童时期出现：我们可以阐明低龄儿童“炎症”的原因，以及细胞因子风暴为什么会升高。我们在这项研究中得到了有趣的结果。

The purposes in this study were to analyze serum proteins for both acute and convalescent phases in the patients with hypercytokinemia using the proteome method which was comprehensive protein analytical method, In this study, the following findings should be elucidated.(1) The mechanism of inflammation -Search of the cause of the cytokine storm-Finally, we could identify original protein in this study in various inflammatory diseases, and we are planning to increase the number of the specimens and to perform the addition tests now.(2) A function of inflammatory cytokine and condition of a patient of " cytokine storm: We analyzed various proteins about expression, action mechanism of inflammatory cytokine, and accomplish to identify universal protein (under submission to English journal).(3) Cytokine storm to be seen in childhood: We could elucidate what caused "inflammation" of children at a low age and why could a cytokine storm raise. We got the interesting results in this study.