The Relationship between Visceral Fat, Adipoctokines and colorectal neoplasma development evaluated by computed tomography (CT) colonography

•肥胖、内脏脂肪与结直肠肿瘤、癌症（CRC）和腺瘤性息肉（polyp）的风险增加有关。CT结肠镜（CTC）作为一种新的检查工具被广泛应用于结直肠癌筛查。评价结直肠肿瘤、内脏脂肪和脂肪细胞因子的关系。123名同时接受结肠镜检查和CTC检查的患者参加了这项研究。我们将患者分为三组：无病变（NL, n=40）、腺瘤性息肉（polyp, n=41）、早期结直肠癌（eCRC, n=21）和晚期结直肠癌（aCRC, n=21）组。息肉组和结直肠癌组的总脂肪面积（TAA）、TAA指数均显著高于NL组。CT结肠镜检查不仅是诊断结直肠肿瘤的一种有效检查方法，同时也可用于评估内脏肥胖、息肉的危险因素。

• Obesity, visceral fat is associated with increased risks for colorectal neoplasm, cancer (CRC) and adenomatous polyp (polyp). CT colonography(CTC) is adopted as a new examination tool for colorectal cancer screening. Evaluate the relationship among colorectal neoplasm, visceral adiposity and adipocytokines. 123 patients who underwent both colonoscopy and CTC were enrolled in this study. We classified three patient groups: no lesion (NL; n=40), Adenomatous polyp (Polyp; n=41), early colorectal cancer (eCRC; n=21), and advanced CRC (aCRC; n=21) groups. Total adipose area (TAA), TAA index in both polyp and CRC groups were significantly higher than that in the NL. CT colonography could not be an only useful examination to diagnose colorectal neoplasms, but also to evaluated the visceral obesity, risk factor of polyp, at the same time.