Identification of genetic factors that define behavioral differences, and study on their ecological significance for social formation

种内行为特性的变化不仅受后天环境的影响，还受遗传因素的影响。然而，对种内行为差异的遗传基础却很少关注。Medaka （Oryzias latipes）具有很高的种内遗传多样性。我们寻找与行为性状相关的基因位点，因为medaka菌株之间存在一些行为差异。本研究以HNI-II和HdrR-II两种自交系菌株为实验对象，对其视觉刺激进行了比较。结果表明，HNI-II的应答率高于HdrR-II，但适应性较低。接下来，我们对HNI-II和HdrR-II之间的F2个体进行了数量性状位点（QTL）分析。结果表明，16号染色体上存在“非适应性”相关位点。

Intraspecific variety of behavioral properties is affected by not only postnatal environments, but also genetic factors. Little attention, however, has been paid on the genetic basis underlying intra-species behavioral difference. Medaka (Oryzias latipes) has high intraspecific genetic variety. We have searched for genetic loci related to behavioral traits, as there are some behavioral differences among medaka strains. Here we presented visual stimuli to two inbred strains, HNI-II and HdrR-II, and compared their responses. As a result, HNI-II showed higher response rate and lower adaptation than HdrR-II. Next, we performed quantitative trait loci (QTL) analysis with F2 individuals between HNI-II and HdrR-II. The result suggested the presence of “un-adaptivity” related loci onchromosome 16.