Analysis of polyamine regulation systems in plants and exploration of functional molecules based on polyamine structure

多胺不仅在植物的发育过程中起重要作用，而且在植物的各种环境胁迫反应中也起重要作用。为了阐明水稻中多胺的动态平衡和作用的调控系统，本研究以水稻中多胺降解酶--多胺氧化酶（PAO）为研究对象，鉴定了水稻中主要PAO的三个不同编码基因。这些蛋白定位于过氧化物酶体并催化多胺的转化。此外，还发现常见的四胺之一热精胺与精胺一样作为信号分子参与抗病。

Polyamines are important not only for developmental processes but also for various environmental stress responses in plants. In order to elucidate the regulatory system responsible for polyamine homeostasis and action, I focused on polyamine degradationenzyme, polyamine oxidase (PAO), and identified three different genes coding for main PAOs in rice. These proteins were localized to peroxisomes and catalyzed polyamine back conversion. Moreover, it was found that one of the common tetraamines, thermospermine, is involved in disease resistance as a signal molecule like spermine.