Mesoporous diamond spherical particles for HPLC column packing materials

采用喷雾干燥和微波等离子体辅助化学气相沉积（MPCVD）技术制备了微米级多孔金刚石球形颗粒（PDSPs）。氮气吸附实验表明，由5 nm爆轰ND颗粒制备的PDSP的BET比表面积约为300m2/g，孔径分布在10 nm附近较窄。另一方面，由直径为20 ~ 50 nm的ND颗粒制备的PDSP的平均孔径为4.6 ~ 9.3 nm，这应该是基于ND的颗粒间空间。利用光化学方法对PDSP表面进行了十八烷基修饰。在反相高效液相色谱（HPLC）柱中成功地使用了填充改性PDSP的色谱柱，并在水/乙腈混合流动相中成功地分离了有机化合物。

Micrometer-sized porous diamond spherical particles (PDSPs) were fabricated from nanodiamond (ND) particles using spray drying and microwave plasma-assisted chemical vapor deposition (MPCVD). Nitrogen gas sorption measurement revealed that the PDSP fabricated from 5 nm detonation ND particles had a BET surface area of ca. 300m2/g and a narrow pore diameter distribution around 10 nm. On the other hand, PDSP fabricated from ND particles with diameters from 20 to 50 nm showed the average pore diameter of 4.6–9.3 nm, which should be based on the interparticle space of the NDs. The PDSP surface was modified with octadecyl groups using a photochemical method. A column packed with the modified PDSP was successfully employed in a reverse phase high performance liquid chromatography (HPLC) column, and the successful separation of organic compounds was demonstrated with a water/acetonitrile mixture mobile phase.