SFB 480: Molecular Biology of Complex Functions in Botanical Systems

所有生物体的发育都是通过核酸、蛋白质和低分子量化合物的相互作用来实现的，它们共同作用，实现了生物体的遗传程序。环境信号是发育的附加调节剂，特别是在植物中。然而，植物发育的分子机制尚不清楚。480合作研究中心旨在更好地了解基因序列中所含的信息是如何通过核酸、蛋白质和低分子量信号分子（如植物激素）之间的相互作用来实现的。为了实现这一目标，广泛的技术被用于在分子水平上研究植物发育的功能方面。这些技术包括：蛋白质生物化学、生物物理和光谱学、分子遗传学、免疫学、植物化学、细胞学和细胞生物学。研究对象范围从蓝藻到酵母和丝状真菌到高等植物包括拟南芥。研究概念被细分为三个类别，代表日益复杂的组织水平：(1)从分子到功能性超分子复合物（项目类别C）；（二）从那些到建立细胞器和细胞隔室（项目乙类）；(3)从细胞到组织再到多细胞生物（项目a类）。

The development of all organisms is realized by interactions of nucleic acids, proteins and low molecular weight compounds which, acting together, realize an organism¿s genetic program. Environmental signals serve as additional modifiers of development, especially in plants. However, the molecular mechanisms underlying plant development, are far from being understood. The collaborative research centre 480 aims at a better understanding of how the information contained in the gene sequences is being realized by an interplay between the nucleic acids, proteins and low molecular weight signaling molecules, such as the plant hormones. In order to achieve this, a wide array of techniques is being used to study functional aspects of plant development at the molecular level. These include techniques of: protein biochemistry, biophysics and spectroscopy, molecular genetics, immunology, phytochemistry, cytology and cell biology. The objects studied range from cyanobacteria to yeasts and filamentous fungi to higher plants including Arabidopsis thaliana. The research concept is subdivided into three categories representing organizational levels of increasing complexity: (1) from molecules to functional supramolecular complexes (project category C); (2) from those to the establishment of organelles and cellular compartments (project category B); (3) from cells to tissues to a multicellular organism (project category A).