GRK 1508: Arterial Remodelling

心血管研究培训集团EuCAR建立在邻近(不到30公里)的独特资产和RWTH亚琛大学和马斯特里赫特大学之间广泛和互补的双边合作网络的坚实基础上。鉴于心血管疾病对西方社会发病率和死亡率的巨大意义及其对公共卫生经济的影响，EuCAR研究方案集中在大血管病理生物学和病理生理学基础上，即动脉重构、动脉粥样硬化及其炎症成分。主要目标是从相关领域引入高度相关的新的细胞和分子靶点，例如免疫介质和生长因子。这与DFG研究单位809(心血管病因学中的趋化因子和黏附分子)和专门的心血管研究所马斯特里赫特(CARIM)认可的科学环境非常一致。重点放在申请者的最佳选择上，这些申请者的特点是：高被引用的出版物的良好平衡的记录，以及在该领域拥有多本出版物的杰出博士、医学/博士或医学博士毕业生的近期历史，以及为博士生或博士后提供的过多资金，以补充研究培训小组。在严格的双边方法中，每个项目将由至少一名来自亚琛和一名来自马斯特里赫特的申请者指导，这不仅将组成一个共享的论文委员会，还将包括成功的终身教职跟踪助理的非分级参与，以密切和综合地指导和监督毕业生并向指导委员会提交报告。招聘过程将包括DFG国际办事处、最初的客座奖学金和面试程序，以评估个人背景并确定个人资格简介，参与推荐的模块。教学方案不仅以亚琛和加勒比的博士方案为基础，还将实施具体的单元和软技能培训，并将通过大师班、系列讲座、国际年度讲习班以及助理指导和研究生组织的活动(如电子学习方法和虚拟显微镜平台)横向联系起来。为了进行评估并顺利获得双学位毕业，将实行学分制和先进的出版要求标准，这些标准将遵循博士学位研究中心的指导方针，该中心是在DFG卓越倡议期间在莱特茅斯大学成立的。

The Cardiovascular Research Training Group EuCAR builds on the unique asset of a close proximity (less than 30 km) and the solid foundation of an extensive and complementary network of bilateral collaborations between the RWTH Aachen and Maastricht Universities. Given the enormous significance of cardiovascular disease for the morbidity and mortality in western societies and its impact on public health economy, the EuCAR research programme is focussed on the underlying macrovascular pathobiology and pathophysiology, namely arterial remodelling, atherosclerosis and its inflammatory components. A main goal is to introduce novel cellular and molecular targets of high relevance from related fields, e.g. immune mediators and growth factors. This is in excellent accordance with the scientific environment endorsed by the DFG Research Unit 809 (Chemokines and Adhesion Molecules in Cardiovascular Pathogenesis) and the dedicated Cardiovascular Research Institute Maastricht (CARIM). Emphasis is placed on optimal selection of applicants, which feature a well-balanced record of highly cited publications and evenly matched recent history of outstanding PhD, MD/PhD or MD graduates with multiple publications in the field, and a plethora of funding for PhD students or post-docs complementing the Research Training Group.In a strictly bilateral approach, each project will be guided by at least one applicant from Aachen and one from Maastricht, which will not only form a shared thesis committee but will include a non-hierarchical involvement of successful tenure-track assistants for close and integrative mentoring and supervision of graduates and reports to the steering committee. The recruitment process will encompass international DFG offices, initial guest scholarships and an interview process to assess individual backgrounds and to define individual qualifying profiles with participation in recommended modules. The teaching programme is not only based on two columns, the PhD programme in Aachen and at CARIM, but will also implement specific modules and soft skill training, and will be horizontally interlinked by master classes, lecture series, international annual workshop meetings, as well as assistant-guided and graduate-organised activities, e.g. an eLearning methods and virtual microscopy platform. For evaluation and successful graduation with a double degree, a credit point system and advanced publication requirement criteria will be imposed, which are oriented along the guidelines for the Centre for Doctorate Studies inaugurated at the RWTH during the DFG Excellence initiative.